3-[(6-Amino-5-(3,4,5-trimethoxyphenyl)-3-pyridinyl]phenol
K02288
CAS: 1431985-92-0
Molecular Formula: C20H20N2O4
3-[(6-Amino-5-(3,4,5-trimethoxyphenyl)-3-pyridinyl]phenol - Names and Identifiers
3-[(6-Amino-5-(3,4,5-trimethoxyphenyl)-3-pyridinyl]phenol - Physico-chemical Properties
| Molecular Formula | C20H20N2O4 |
| Molar Mass | 352.38 |
| Density | 1.232±0.06 g/cm3(Predicted) |
| Melting Point | 201-203°C |
| Boling Point | 522.2±50.0 °C(Predicted) |
| Solubility | DMSO (Slightly), Methanol (Slightly) |
| Appearance | powder |
| Color | white to beige |
| pKa | 9.33±0.10(Predicted) |
| Storage Condition | 2-8°C |
| In vitro study | K02288 dose-dependently inhibited BMP4-and bmp6-induced Smad1/5/8 phosphorylation in C2C12 cells without affecting TGF-β-BMP signaling. K02288 dose-dependently inhibited Smad1/5/8 phosphorylation in BMP4-and bmp6-induced C2C12 cells without affecting TGF-β-BMP signaling. |
| In vivo study | In zebrafish embryos, K02288 dose-dependently induced the dorsal phenotype without affecting the formation of vascular space (ISV). in zebrafish embryos, K02288 dose-dependently induced a dorsal phenotype without affecting the formation of vascular space (ISV). |
3-[(6-Amino-5-(3,4,5-trimethoxyphenyl)-3-pyridinyl]phenol - Risk and Safety
| UN IDs | UN 2811 6.1 / PGIII |
3-[(6-Amino-5-(3,4,5-trimethoxyphenyl)-3-pyridinyl]phenol - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.838 ml | 14.189 ml | 28.378 ml |
| 5 mM | 0.568 ml | 2.838 ml | 5.676 ml |
| 10 mM | 0.284 ml | 1.419 ml | 2.838 ml |
| 5 mM | 0.057 ml | 0.284 ml | 0.568 ml |
Last Update：2024-01-02 23:10:35
3-[(6-Amino-5-(3,4,5-trimethoxyphenyl)-3-pyridinyl]phenol - Introduction
K02288 is an organic compound whose chemical name is 2-((1H-pyridin-3-yl)methyl)-4-quinazolinamine. The following is an introduction to the nature, use, preparation and safety information of K02288:
Nature:
K02288 is a white crystalline solid with inherent pharmaceutical properties. It is a Tyrosine Kinase (Tyrosine Kinase) inhibitor and has an inhibitory effect on the synthesis of tyramine from acetyl coenzyme A using Tyrosine.
Use:
K02288 is commonly used as a research tool and plays an important role in the study of tumor biology and cell signal transduction pathways. The compounds can be used to study the function and mechanism of kinase signal transduction pathways, especially for proteins with tyrosine kinase activity.
Preparation Method:
The preparation method of K02288 is very complicated and requires a series of synthesis steps. The general preparation method mainly depends on the technology and means of organic synthetic chemistry. The process of preparing K02288 requires high purity raw materials and rigorous experimental procedures.
Safety Information:
K02288 is a compound commonly used in laboratories, but it may pose certain risks to human health. Use and handle K02288 with appropriate personal protective equipment such as laboratory gloves and goggles. In addition, work in a well-ventilated laboratory environment to avoid inhaling dust or contact with skin and eyes. If ingested or inhaled, seek medical attention immediately. When using K02288, according to the needs of the experiment and the specific situation, it is necessary to strictly abide by the relevant safety operation procedures.
Nature:
K02288 is a white crystalline solid with inherent pharmaceutical properties. It is a Tyrosine Kinase (Tyrosine Kinase) inhibitor and has an inhibitory effect on the synthesis of tyramine from acetyl coenzyme A using Tyrosine.
Use:
K02288 is commonly used as a research tool and plays an important role in the study of tumor biology and cell signal transduction pathways. The compounds can be used to study the function and mechanism of kinase signal transduction pathways, especially for proteins with tyrosine kinase activity.
Preparation Method:
The preparation method of K02288 is very complicated and requires a series of synthesis steps. The general preparation method mainly depends on the technology and means of organic synthetic chemistry. The process of preparing K02288 requires high purity raw materials and rigorous experimental procedures.
Safety Information:
K02288 is a compound commonly used in laboratories, but it may pose certain risks to human health. Use and handle K02288 with appropriate personal protective equipment such as laboratory gloves and goggles. In addition, work in a well-ventilated laboratory environment to avoid inhaling dust or contact with skin and eyes. If ingested or inhaled, seek medical attention immediately. When using K02288, according to the needs of the experiment and the specific situation, it is necessary to strictly abide by the relevant safety operation procedures.
Last Update：2024-04-09 20:52:54
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Product Name: K02288 Visit Supplier Webpage Request for quotationCAS: 1431985-92-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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